Author

H. Knutsdottir

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

B. Dunkerly-Eyring· 1 shared B. O'Rourke· 1 shared C. Hodgdon· 1 shared C. U. Oeing· 1 shared D. A. Kass· 1 shared D. Ashok· 1 shared D. C. Sarver· 1 shared D. D. Sears· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPhysiology

B. Dunkerly-Eyring

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A comprehensive single-cell breast tumor atlas defines cancer epithelial and immune cell heterogeneity and interactions predicting anti-PD-1 therapy response

L. Xu, K. N. Saunders, H. Knutsdottir, K. Chen, J. Maues, C. Hodgdon, E. T. Roussos-Torres, S. Reddy, L. Xu, I. S. Chan

The paper defines cancer epithelial and immune cell heterogeneity in breast tumors using single-cell RNA-seq and develops a tool to predict anti-PD-1 therapy response.

bioRxiv · Aug 1, 2022 · PreprintCancer Biology

PDE9 Inhibition Activates PPARa to Stimulate Mitochondrial Fat Metabolism and Reduce Cardiometabolic Syndrome

S. Mishra, V. Hahn, N. Sadagopan, B. Dunkerly-Eyring, S. Rodriguez, D. C. Sarver, R. P. Ceddia, S. Murphy, H. Knutsdottir, V. Jani, D. Ashok, C. U. Oeing, B. O'Rourke, K. Sharma, J. Gangoiti, , D. A. Kass

This study shows PDE9 inhibition activates PPARa to enhance mitochondrial fat metabolism and reduce cardiometabolic syndrome in mice, with potential for treating obesity in men and postmenopausal women.

bioRxiv · Feb 2, 2021 · PreprintPhysiology