Author

L. Leung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Apffel· 1 shared A. D'Andrea· 1 shared A. Gonzalez· 1 shared A. J. Bass· 1 shared A. Rosenthal· 1 shared A. Tserniak· 1 shared B. Gaeta· 1 shared D. Maslyar· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Apffel

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2 papers

Recent·Most cited

The multi-Siglec inhibitor AL009 reprograms suppressive macrophages and activates innate and adaptive tumor immunity

S. C. Nalle, H. Lam, L. Leung, S. Liang, D. Maslyar, A. Rosenthal

AL009, a multi-Siglec inhibitor, reprograms suppressive macrophages and enhances anti-tumor immunity in preclinical models.

bioRxiv · Aug 2, 2023 · PreprintCancer Biology

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

E. Chan, T. Shibue, J. McFarland, B. Gaeta, J. McPartlan, M. Ghandi, J. B. Liu, J.-B. Lazaro, N. Dumont, A. Gonzalez, A. Apffel, S. O. Ali, L. Leung, E. Roberts, E. Rizvochenko, , A. J. Bass

The paper identifies WRN helicase as a synthetic lethal target in microsatellite unstable cancers through CRISPR/Cas9 and RNAi screens, showing its essentiality in MSI cell lines.

bioRxiv · Dec 21, 2018Cancer Biology