PhysiologybioRxiv
Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption
C.-C. Tang, C. Castro, M. J. O'Meara…·M. N. Wein
The paper shows that YKL-05-099, which inhibits SIKs and CSF1R, increases bone formation without increasing bone resorption in mice.
DOI 10.7554/elife.67772