Computational design of N-linked glycans for high throughput epitope profiling
P. J. Greisen, L. Yi, R. Zhou, J. Zhou, E. Johansson, T. Dong, H. Liu, L. B. Johnsen, S. Lund, L. A. Svensson, H. Zhu, N. Thomas, Z. Yang, H. Ostergaard
The paper develops a computational method using N-linked glycans to rapidly map epitopes, validated through ELISA, yeast display, and X-ray crystallography using human coagulation factor IXa.
Protein Science · Sep 26, 2023Peer-reviewedBioengineering