Author

H. Powell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Pekosz· 3 shared H. Liu· 2 shared A. Ansari· 1 shared A. Brady· 1 shared A. Callaway· 1 shared A. Donaldson· 1 shared A. Dugas· 1 shared A. DuVal· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

A. Pekosz

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Classification of Variants of Reduced Penetrance in High Penetrance Cancer Susceptibility Genes: Framework for Genetics Clinicians and Clinical Scientists by CanVIG-UK (Cancer Variant Interpretation Group-UK)

Alice Garrett, Sophie Allen, Miranda Durkie, George J. Burghel, Rachel Robinson, Alison Callaway, Joanne Field, Bethan A. Frugtniet, Sheila Palmer-Smith, Jonathan Grant, Judith Pagan, Trudi McDevitt, Charlie F Rowlands, Terri Patricia McVeigh, Helen Hanson, , J. Williams

The paper develops a framework for classifying variants of reduced penetrance in cancer susceptibility genes to improve variant interpretation consistency.

Genetics in Medicine · Oct 24, 2024Peer-reviewedGenetic & Genomic Medicine

HA and M2 sequences alter the replication of 2013-16 H1 Live Attenuated Influenza Vaccine Infection in Human Nasal Epithelial Cell cultures

J. D. Resnick, L. M. Canaday, H. Liu, H. Powell, A. M. McCoy, D. Nguyen, A. Pekosz

The paper compares replication of H1 LAIVs with different HA and M2 sequences in human nasal epithelial cells, finding HA differences impact replication and immune response.

bioRxiv · Nov 11, 2021Microbiology

Neuraminidase antigenic drift of influenza A virus H3N2 clade 3c.2a viruses alters virus replication, enzymatic activity and inhibitory antibody binding

H. Powell, A. Pekosz

This study examines how a novel N-linked glycosylation in the neuraminidase protein of H3N2 influenza viruses affects viral replication, enzymatic activity, and antibody binding.

PLOS Pathogens · Jun 29, 2020Peer-reviewedMicrobiology

Identification of H3N2 NA and PB1-F2 genetic variants and their association with disease symptoms in the 2014-15 influenza season

D. Blumenkrantz, T. Mehoke, J. Hardick, K. Shaw-Saliba, H. Powell, N. Wohlgemuth, H. Liu, E. Macias, J. Evans, M. Lewis, R. Medina, L. M. Sauer, A. Dugas, A. DuVal, A. P. Lane, , A. Pekosz

The paper identifies H3N2 NA and PB1-F2 genetic variants and links their presence to increased cough and shortness of breath in patients during the 2014-15 influenza season.

bioRxiv · Feb 20, 2020Microbiology