Author

H. S. Hasdemir

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

E. Karakas· 1 shared E. Tajkhorshid· 1 shared H. Mchaourab· 1 shared M. Sinclair· 1 shared Q. Tang· 1 shared R. A. Stein· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

E. Karakas

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1 paper

Recent·Most cited

BiophysicsbioRxivMay 29, 2023

Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter

Q. Tang, M. Sinclair, H. S. Hasdemir…·H. Mchaourab

This study uses cryo-EM, DEER, and MD simulations to analyze the conformational dynamics of BmrCD, revealing asymmetric ATP and substrate interactions that drive its transport cycle.

DOI 10.1038/s41467-023-42937-5

cryo-EMmicroscopy & imaging analysis

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