Transcriptomes and metabolism define mouse and human MAIT cell heterogeneity
S. Chandra, G. Ascui, T. Riffelmacher, A. Chawla, C. Ramirez-Suastegui, V. C. Castelan, G. Seumois, H. Simon, M. P. Murray, G.-Y. Seo, A. L. R. Premlal, G. Verstichel, Y. Li, C.-H. Lin, J. Greenbaum, , M. Kronenberg
This study identifies MAIT cell heterogeneity in mice and humans through single-cell RNA sequencing and metabolic analysis, revealing distinct transcriptomes and metabolic states in different tissues and species.
bioRxiv · Dec 20, 2021 · PreprintImmunology