Author

A. Chawla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:metabolism & bioenergetics· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. L. R. Premlal· 1 shared A. Matettore· 1 shared A. Rothrauff· 1 shared A. V. Joglekar· 1 shared C. H. Ottensmeier· 1 shared C. Ramirez-Suastegui· 1 shared C.-H. Lin· 1 shared D. Chen· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

A. L. R. Premlal

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Author profile →

5 papers

Recent·Most cited

Temporal dynamics and genomic programming of plasma cell fates

G. K. M. Vijay, M. Zhou, K. Thakkar, A. Rothrauff, A. Chawla, D. Chen, L. Lau, P. Habib, K. Chetal, P. Chhibbar, J. Fan, J. Das, A. V. Joglekar, L. Borghesi, N. Salomonis, , H. Singh

This study identifies a novel PC transition state and shows that long-lived plasma cells arise from late-phase GC responses through TIGIT-dependent clonal expansion.

bioRxiv · Aug 27, 2023 · PreprintImmunology

Trade-Offs Between Hepatic Host Defense and Metabolic Programs Underlie Sex-Biased Diseases

J. Nikkanen, Y. A. Leong, W. C. Krause, D. Dermadi, J. A. Maschek, T. Van Ry, J. Cox, E. Weiss, O. Gokcumen, A. Chawla, H. Ingraham

This study identifies a sex-dependent trade-off between hepatic host defense and metabolic programs in mice, showing that BCL6 protects males from infection but increases metabolic disease risk under dietary excess.

bioRxiv · Jan 7, 2022Physiology

Transcriptomes and metabolism define mouse and human MAIT cell heterogeneity

S. Chandra, G. Ascui, T. Riffelmacher, A. Chawla, C. Ramirez-Suastegui, V. C. Castelan, G. Seumois, H. Simon, M. P. Murray, G.-Y. Seo, A. L. R. Premlal, G. Verstichel, Y. Li, C.-H. Lin, J. Greenbaum, , M. Kronenberg

This study identifies MAIT cell heterogeneity in mice and humans through single-cell RNA sequencing and metabolic analysis, revealing distinct transcriptomes and metabolic states in different tissues and species.

bioRxiv · Dec 20, 2021 · PreprintImmunology

Cell culture-based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system

M. D. Hein, A. Chawla, M. Cattaneo, S. Y. Kupke, Y. Genzel, U. Reichl

This paper establishes an automated perfusion process for producing IAV DIPs using an alternating tangential flow filtration system, achieving high DIP titers and enabling continuous virus harvesting.

bioRxiv · Jun 7, 2021Bioengineering

Arterial carboxyhaemoglobin levels in children admitted to PICU: a retrospective observational study

A. Chawla, S. Ray, A. Matettore, M. Peters

This study examines COHb levels in critically ill children, finding higher levels in younger patients and associations with longer ventilation and mortality.

bioRxiv · Dec 7, 2018Physiology