Author

Hervé Lecoeur

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Eric PrinaiD· 3 shared Hugo VaretiD· 3 shared Charfeddine GharsallahiD· 2 shared Gerald Frank SpäthiD· 2 shared Rachel LegendreiD· 2 shared Adina A. Baniahmad· 1 shared Antonello MaiiD· 1 shared Astrid Bruckmann· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCell Biology

Eric PrinaORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintMar 24, 2024

MAPPING CHANGES OF MIRNA-MRNA NETWORKS IN LEISHMANIA-INFECTED MACROPHAGES PREDICTS REGULATORY MIRNA-TF LOOPS AS NOVEL TARGETS OF PARASITE IMMUNE SUBVERSION

Charfeddine Gharsallah, Hervé Lecoeur, Hugo Varet…·Gerald Frank Späth

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintSep 29, 2023

Inhibition of the macrophage demethylase LSD1 reverses Leishmania amazonensis-induced transcriptomic changes and causes a decrease in parasite load

Maria Gutiérrez-Sanchez, Adina A. Baniahmad, Charfeddine Gharsallah…·Gerald Frank Späth

This study shows that inhibiting LSD1 in macrophages reduces Leishmania parasite load and reverses infection-induced transcriptomic changes.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintMay 24, 2019

Leishmania targets the macrophage epigenome and dampens the NF-κB/NLRP3- mediated inflammatory response

Hervé Lecoeur, Eric Prina, Thibault Rosazza…·Gerald F. Späth

This study shows Leishmania amazonensis modulates macrophage epigenetics to suppress NF-κB and NLRP3 inflammasome activation, aiding parasite survival.

DOI 10.1101/649632

humanbulk RNA-seq

𝕏 PostBluesky