Enhanced detection of low-expressed miRNAs in Leishmania-infected macrophages through RNA fractionation and RT-qPCR optimization
Sara Maestrini, H. Lecoeur, Charfeddine Gharsallah…·Eric Prina
Author
InsermORCID 0000-0002-6888-8777Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Sara Maestrini, H. Lecoeur, Charfeddine Gharsallah…·Eric Prina
Charfeddine Gharsallah, Hervé Lecoeur, Hugo Varet…·Gerald Frank Späth
Maria Gutiérrez-Sanchez, Adina A. Baniahmad, Charfeddine Gharsallah…·Gerald Frank Späth
This study shows that inhibiting LSD1 in macrophages reduces Leishmania parasite load and reverses infection-induced transcriptomic changes.
Despina Smirlis, Florent Dingli, Pascale Pescher…·Gerald Frank Späth
This study uses SILAC-based proteomics to identify 86 differentially expressed proteins in murine macrophages infected with Leishmania donovani, revealing changes in host metabolism and lysosomal organization.
Hervé Lecoeur, Eric Prina, Thibault Rosazza…·Gerald F. Späth
This study shows Leishmania amazonensis modulates macrophage epigenetics to suppress NF-κB and NLRP3 inflammasome activation, aiding parasite survival.