Author

Charfeddine Gharsallah

InsermORCID 0000-0003-2548-0509Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Bioinformatics· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Eric PrinaiD· 3 shared Gerald Frank SpäthiD· 3 shared Hervé Lecoeur· 2 shared Hugo VaretiD· 2 shared Rachel LegendreiD· 2 shared Adina A. Baniahmad· 1 shared Ahmed Fakhfakh· 1 shared Amel RehaiemiD· 1 shared

Activity by Year

2023-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMolecular Biology

Eric PrinaORCID

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5 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 20, 2025

Enhanced detection of low-expressed miRNAs in Leishmania-infected macrophages through RNA fractionation and RT-qPCR optimization

Sara Maestrini, H. Lecoeur, Charfeddine Gharsallah…·Eric Prina

DOI 10.1101/2025.08.20.671241

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivPreprintOct 19, 2024

Impact of methicillin resistance on virulence factor expression in 1 Staphylococcus aureus: Insights from gene expression profiling

Charfeddine Gharsallah, Asma Ferjani, Mouna Ghariani…·Ilhem Boutiba-Ben Boubaker

This study examines the relationship between methicillin resistance and virulence factor expression in Staphylococcus aureus strains using gene expression profiling.

DOI 10.1101/2024.10.19.619075

humanDNA methylation

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BioinformaticsbioRxivPreprintJun 13, 2024

Plant miRNAs Anti-Staphylococcus aureus: Therapeutic Perspective

Charfeddine Gharsallah

The paper identifies plant miRNAs that could target S. aureus's agr system and mecA gene through in silico analysis, proposing them as potential alternative therapies.

DOI 10.1101/2024.06.13.598803

statistical model

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MicrobiologybioRxivPreprintMar 24, 2024

MAPPING CHANGES OF MIRNA-MRNA NETWORKS IN LEISHMANIA-INFECTED MACROPHAGES PREDICTS REGULATORY MIRNA-TF LOOPS AS NOVEL TARGETS OF PARASITE IMMUNE SUBVERSION

Charfeddine Gharsallah, Hervé Lecoeur, Hugo Varet…·Gerald Frank Späth

2 citations

mousebulk RNA-seq

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Cell BiologybioRxivPreprintSep 29, 2023

Inhibition of the macrophage demethylase LSD1 reverses Leishmania amazonensis-induced transcriptomic changes and causes a decrease in parasite load

Maria Gutiérrez-Sanchez, Adina A. Baniahmad, Charfeddine Gharsallah…·Gerald Frank Späth

This study shows that inhibiting LSD1 in macrophages reduces Leishmania parasite load and reverses infection-induced transcriptomic changes.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky