De Novo Design of Integrin α5β1 Modulating Proteins for Regenerative Medicine
X. Wang, J. Guillem-Marti, S. Kumar, D. Lee, D. Cabrerizo-Aguado, R. Werther, K. A. E. Alamo, Y.-T. Zhao, A. Nguyen, I. Kopyeva, B. Huang, J. Li, Y. Hao, X. Li, A. Brizuela-Velasco, , D. Baker
The paper designs de novo proteins called NeoNectins that specifically bind integrin α5β1, enhancing cell attachment and tissue integration in biomaterials.
bioRxiv · Jun 21, 2024Bioengineering