Author

I. Samuel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Baker· 1 shared A. Elad· 1 shared A. Kumar· 1 shared A. Permyakova· 1 shared A. W. Norris· 1 shared C. A. Kulkarni· 1 shared C. Kang· 1 shared C. My-Ta· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

A. Baker

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Author profile →

2 papers

Recent·Most cited

Inhibition of somatostatin enhances the long-term metabolic outcomes of sleeve gastrectomy in mice

D. Kleiman, Y. Arad, S. Azulai, A. Baker, M. Bergel, A. Elad, L. Hefetz, H. Israeli, M. Littor, A. Permyakova, I. Samuel, J. Tam, R. Ben-Haroush Schyr, D. Ben-Zvi

This study shows that inhibiting somatostatin signaling improves and sustains metabolic benefits after sleeve gastrectomy in mice.

bioRxiv · Apr 11, 2023Physiology

Small molecule SWELL1-LRRC8 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes

S. K. Gunasekar, L. Xie, P. R. Chheda, C. Kang, D. M. Kern, C. My-Ta, A. Kumar, J. M. Maurer, E. E. Gerber, W. J. Grzesik, M. Elliot-Hudson, Y. Zhang, C. A. Kulkarni, I. Samuel, J. K. Smith, , R. Sah

This study identifies small molecule modulators of the SWELL1-LRRC8 complex that improve glycemic control and prevent NAFLD in murine T2D by restoring insulin signaling and secretion.

Nature Communications · Feb 10, 2022Peer-reviewedPhysiology