ImmunologybioRxivPreprint
Jagged1 overexpression on T cells induces thymic regulatory T cells leading to thymic involution
J. Kritikou, I. Sanchez-Pascual, J. P. Munoz-Miranda…·B. Chambers
This study identifies Jagged1 overexpression in T cells as a driver of thymic involution through increased regulatory T cells, observed in a mouse model with thymic atrophy.
DOI 10.1101/2022.08.25.504005