Author

I. Sturmlechner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

D. J. Baker· 2 shared A. d. Bruin· 1 shared A. N. Pena· 1 shared A. Ruta· 1 shared A. Tam· 1 shared B. A. Davies· 1 shared B. G. Childs· 1 shared C. Cherry· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

D. J. Baker

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Author profile →

2 papers

Recent·Most cited

HD-PTP/PTPN23 hypomorphic mice display lipodystrophy

B. A. Davies, J. A. Payne, C. P. Martin, D. Schultz, B. G. Childs, C. Zhang, K. Jeganathan, I. Sturmlechner, T. A. White, A. d. Bruin, H. Chen, M. A. Davies, S. Jachim, N. K. LeBrasseur, R. C. Piper, , D. J. Katzmann

This study shows that hypomorphic HD-PTP/PTPN23 mice develop lipodystrophy and reduced adipogenesis, indicating HD-PTP's role in insulin signaling and fat accumulation.

bioRxiv · Aug 2, 2022 · PreprintCell Biology

Transfer learning of an in vivo-derived senescence signature identifies conserved and tissue-specific senescence across species and diverse pathologies

C. Cherry, J. I. Andorko, K. Krishnan, J. C. Mejias, H. H. Nguyen, K. B. Stivers, E. F. Gray-Gaillard, A. Ruta, N. Hamada, M. Hamada, I. Sturmlechner, S. Trewartha, J. H. Michel, L. D. Huyer, M. T. Wolf, , J. H. Elisseeff

The paper develops a transfer learning approach to identify senescent cells across species and tissues using an in vivo-derived gene expression signature, revealing conserved and tissue-specific senescence features.

bioRxiv · Mar 22, 2022 · PreprintBioengineering