Cancer BiologybioRxiv
Rate volatility and asymmetric segregation diversify mutation burden in mutator cells.
I. T. Dowsett, J. Sneeden, B. Olson…·A. J. Herr
The paper models how mutator phenotypes in budding yeast increase genetic heterogeneity through rate volatility and asymmetric mutation segregation.
DOI 10.1038/s42003-020-01544-6