Author

I. T.-L. Wong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:clustering· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

J. Luebeck· 2 shared J. T. Lange· 2 shared P. S. Mischel· 2 shared V. Bafna· 2 shared A. G. Henssen· 1 shared A. Tiwari· 1 shared B. J. He· 1 shared B. Werner· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

J. Luebeck

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 18, 2023

Coordinated inheritance of extrachromosomal DNA species in human cancer cells

K. L. Hung, M. G. Jones, I. T.-L. Wong…·H. Y. Chang

This study shows that multiple extrachromosomal DNA species are coordinately inherited in cancer cells through mitotic co-segregation, enabling oncogene cooperation and guiding therapeutic strategies.

DOI 10.1101/2023.07.18.549597

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 18, 2021

The landscape of extrachromosomal circular DNA in medulloblastoma

O. S. Chapman, J. Luebeck, S. Wani…·L. Chavez

This study identifies ecDNA in 18% of medulloblastoma patients, linking it to higher relapse and mortality rates and suggesting enhancer rewiring as an oncogenic mechanism.

DOI 10.1101/2021.10.18.464907

humanwhole-genome sequencing

𝕏 PostBluesky