A. Tiwari

Lipid Specificity of the Fusion of Bacterial Extracellular Vesicles with the Host Membrane

This study investigates how bacterial extracellular vesicles interact with host lipid membranes, showing they increase membrane fluidity and preferentially bind to liquid-disordered regions.

Investigating bacteria-phage interaction dynamics using droplet-based technology

This study uses droplet microfluidics and fluorescence microscopy to analyze bacterial-phage interactions in E. coli, revealing growth and lysis dynamics of phage-infected cells.

Label-free analysis of bacterial growth and lysis at the single-cell level using droplet microfluidics and object detection-oriented deep learning

This paper develops a label-free method using microfluidics and YOLOv4 deep learning to count and track single bacterial cells and study phage interactions.

Flat clathrin lattices are linked to metastatic potential in colorectal cancer

The paper shows that flat clathrin lattices are more prevalent in colorectal cancer cells with higher metastatic potential.

Extraction and characterization of cellulose from invasive weeds from central Nepal: A potential prospect of environmental management.

This study extracts and characterizes cellulose from invasive weeds in Nepal, showing it can be used as a sustainable alternative to plastics and textiles.

Enhancement of mitochondrial function fosters B cell immune memory

This study shows that enhancing mitochondrial function with Mdivi-1 improves memory B cell differentiation and vaccine efficacy against influenza and SARS-CoV-2.

Structural characterization of a breast cancer-associated mutation in caveolin-1

This study examines how a breast cancer-associated mutation in CAV1, P132L, affects its structure and oligomerization, revealing its impact on caveolae formation.

Biomechanical and biochemical assessment of YB-1 expression in melanoma cells

This study assesses how YB-1 expression affects biomechanical and biochemical properties of melanoma cells, finding YB-1 knock-out cells are softer and lack key mesenchymal markers.

Recording true oxygen reduction capacity during photosynthetic electron transfer in Arabidopsis thylakoids and intact leaves

The paper quantifies oxygen reduction and H2O2 accumulation in thylakoids and leaves, showing H2O2 accumulates at Photosystem I and may enhance mitochondrial respiration during stress.

The landscape of extrachromosomal circular DNA in medulloblastoma

This study identifies ecDNA in 18% of medulloblastoma patients, linking it to higher relapse and mortality rates and suggesting enhancer rewiring as an oncogenic mechanism.

In vitro reconstitution demonstrates the amyloid-beta mediated myelin membrane deformation

This study shows A{beta}-40 induces myelin membrane tubulation in vitro through binding and aggregation, revealing mechanisms of potential neuronal demyelination in Alzheimer's Disease.

Captivity-induced behaviour and spatial learning abilities in an enigmatic, aquifer-dwelling blind eel, Rakthamichthys digressus

This study examines how captivity affects behavior and spatial learning in the blind eel Rakthamichthys digressus, finding altered behaviors but no change in behavioral syndromes or spatial learning ability.

Ratio of hydrophobic-hydrophilic and positive-negative residues at lipid-water-interface influences surface expression and channel-gating of TRPV1

The paper investigates how the ratio of hydrophobic-hydrophilic and positive-negative charged residues at the lipid-water interface affects TRPV1 surface expression and channel-gating.

Integrated genomic view of SARS-CoV-2 in India

The paper analyzes SARS-CoV-2 genomic data from India to trace introduction and local transmission, identifying multiple clades and highlighting the need for molecular surveillance.

Common Garlic (Allium sativum L.) has Potent Anti-Bacillus anthracis Activity

This study evaluates the anti-Bacillus anthracis activity of common plants, finding that garlic extract shows potent bactericidal effects and stability under various conditions.

PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2.

PT150 inhibits SARS-CoV-2 with EC90 5.55 M in human bronchial epithelial cells by downregulating AR and modulating ACE2 and TMPRSS2.

KLF4 coordinates corneal epithelial apicobasal polarity and plane of cell division, and is downregulated in ocular surface squamous neoplasia

This study shows KLF4 maintains corneal epithelial polarity and division plane, and its loss is linked to ocular surface squamous neoplasia.

Role of HP1β during spermatogenesis and DNA replication

This study investigates the role of Cbx1 in male germ cells and finds that its loss leads to DNA replication defects and increased DNA damage.

A commonly used photosynthetic inhibitor fails to block electron flow to photosystem I in intact systems

The paper investigates the efficacy of DNP-INT as a photosynthetic inhibitor and finds it fails to block electron flow to photosystem I in intact systems.

Discovery of compounds inhibiting the ADP-ribosyltransferase activity of pertussis toxin

This study identifies two small molecules that inhibit the ADP-ribosyltransferase activity of pertussis toxin, showing potential for targeted antibiotic development against Bordetella pertussis.

Increased expression of mitochondrial dysfunction stimulon genes affects chloroplast redox status and photosynthetic electron transfer in Arabidopsis

This study shows that increased MDS gene expression in Arabidopsis affects chloroplast redox status and photosynthetic electron transfer, with hypoxia mitigating these effects in an MDS-overexpressor mutant.

Transient Receptor Potential Ankyrin1 channel is endogenously expressed in T cells and regulates immune functions

This study shows TRPA1 is expressed in T cells and modulates calcium levels and activation markers during T cell stimulation.

PLK1 protects centromeres from BLM-mediated disintegration to promote chromosome biorientation

This study shows PLK1 protects centromeres from BLM-mediated disintegration, which is critical for maintaining chromosome biorientation during mitosis.