Cancer BiologybioRxivPreprint
The landscape of extrachromosomal circular DNA in medulloblastoma
O. S. Chapman, J. Luebeck, S. Wani…·L. Chavez
This study identifies ecDNA in 18% of medulloblastoma patients, linking it to higher relapse and mortality rates and suggesting enhancer rewiring as an oncogenic mechanism.
DOI 10.1101/2021.10.18.464907