Cancer BiologybioRxivPreprint
Evolution of metastases-associated fibroblasts in the lung microenvironment is driven by stage-specific transcriptional plasticity
O. Shani, Y. Raz, L. Monteran…·N. Erez
This study shows lung fibroblasts in breast cancer metastases are transcriptionally dynamic and plastic, with stage-specific gene signatures and Myc as a key regulator linked to poor survival.