Author

I.-M. Sun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

J. D. Powell· 2 shared J. Wen· 2 shared L. Zhao· 2 shared M. L. Arwood· 2 shared A. J. Tam· 1 shared B. S. Slusher· 1 shared C. H. Patel· 1 shared E. A. Thompson· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

J. D. Powell

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Author profile →

2 papers

Recent·Most cited

Persistent CAD activity in memory CD8+ T cells supports rRNA synthesis and ribosomal biogenesis required at rechallenge

M. Claiborne, S. Sengupta, L. Zhao, M. L. Arwood, I.-M. Sun, J. Wen, E. A. Thompson, M. Mitchell-Flack, M. Laiho, J. D. Powell

The paper identifies CAD-induced pyrimidine synthesis and ribosomal biogenesis as critical for rapid recall responses in memory CD8+ T cells.

bioRxiv · Nov 10, 2021Immunology

Targeting glutamine metabolism enhances tumor specific immunity by inhibiting the generation of MDSCs and reprogramming tumor associated macrophages

M.-H. Oh, I.-H. Sun, L. Zhao, R. Leone, I.-M. Sun, W. Xu, S. L. Collins, A. J. Tam, R. L. Blosser, C. H. Patel, J. Englert, M. L. Arwood, J. Wen, Y. Chan-Li, P. Majer, , J. D. Powell

This study shows that targeting glutamine metabolism in tumors reduces MDSC generation, increases inflammatory macrophages, and enhances anti-tumor immunity, making checkpoint-resistant tumors responsive to immunotherapy.

bioRxiv · Jun 3, 2019 · PreprintImmunology