J. A. Coleman

This study reports the cryo-EM structure of VMAT2 bound to tetrabenazine, revealing its inhibition mechanism and conformational dynamics.

This paper introduces a computational method to identify atrial regions susceptible to micro-reentry by modeling percolation-like phenomena on spatial networks of atrial fibre maps.

The paper investigates the binding of paroxetine and its analogs to the serotonin transporter using structural and biochemical methods, revealing how they stabilize the outward-open conformation and inhibit serotonin transport.