ImmunologybioRxiv
Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis
T. P. Burke, P. Engström, R. A. Chavez…·M. D. Welch
This study shows that Rickettsia parkeri is sensitive to type I interferon, which is counteracted by inflammasome-mediated pyroptosis, revealing a trade-off in innate immunity.
DOI 10.1038/s41564-020-0673-5