Author

J. A. Maynard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. W. Nguyen· 3 shared C.-L. Hsieh· 3 shared J. S. McLellan· 3 shared A. M. DiVenere· 2 shared K. C. Le· 2 shared S. M. Costello· 2 shared S. Marqusee· 2 shared S. R. Shoemaker· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersBiochemistry

A. W. Nguyen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of a conserved neutralizing epitope present on spike proteins from all highly pathogenic coronaviruses

Y. Huang, A. W. Nguyen, C.-L. Hsieh, R. Silva, O. S. Olaluwoye, R. Wilen, T. S. Kaoud, L. R. Azouz, A. N. Qerqez, K. C. Le, A. L. Bohanon, A. M. DiVenere, Y. Liu, D. Amengor, S. R. Shoemaker, , J. A. Maynard

The paper identifies a conserved neutralizing epitope on the S2 domain of SARS-CoV, SARS-CoV-2, and MERS-CoV spike proteins that is targeted by antibody 3A3.

eLife · Mar 21, 2023Peer-reviewedBiochemistry

The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes

S. M. Costello, S. R. Shoemaker, H. T. Hobbs, A. W. Nguyen, C.-L. Hsieh, J. A. Maynard, J. S. McLellan, J. E. Pak, S. Marqusee

The paper identifies an alternative open-trimer conformation of the SARS-CoV-2 spike ectodomain that exposes novel epitopes and is modulated by temperature, binding, and sequence variants.

bioRxiv · Jul 11, 2021Biophysics

Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes

C.-L. Hsieh, J. A. Goldsmith, J. M. Schaub, A. M. DiVenere, H.-C. Kuo, K. Javanmardi, K. C. Le, D. Wrapp, A. G.-W. Lee, Y. Liu, C.-W. Chou, P. O. Byrne, C. K. Hjorth, N. V. Johnson, J. Ludes-Meyers, , J. S. McLellan

This study designs and characterizes prefusion-stabilized SARS-CoV-2 spike variants to improve protein yield and stability for vaccine and diagnostic development.

bioRxiv · May 30, 2020Microbiology

Characterizing the innate and adaptive responses of immunized mice to Bordetella pertussis infection using in vivo imaging and transcriptomic analysis

D. T. Boehm, M. E. Varney, T. Y. Wong, E. S. Nowak, E. Sen-Kilic, J. M. Hall, S. D. Bradford, K. A. Begley, J. U. Bevere, M. S. Epperly, J. A. Maynard, E. L. Hewlett, M. Barbier, F. H. Damron

This study uses in vivo imaging and transcriptomic analysis to compare immune responses in mice vaccinated against B. pertussis, finding differential gene expression and neutrophil dynamics across vaccine types.

bioRxiv · Jun 18, 2019 · PreprintImmunology