Author

J. Andrejeva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Vasou· 2 shared C. G. Bamford· 2 shared D. J. Hughes· 2 shared J. McLauchlan· 2 shared R. E. Randall· 2 shared C. Paulus· 1 shared D. Bogunovic· 1 shared D. Holthaus· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

A. Vasou

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Author profile →

2 papers

Recent·Most cited

A co-opted ISG15-USP18 binding mechanism normally reserved for deISGylation controls type I IFN signalling

A. Vasou, K. Nightingale, V. Cetkovska, J. Scheler, C. G. Bamford, J. Andrejeva, U. Schwarz-Linek, R. E. Randall, J. McLauchlan, M. P. Weekes, D. Bogunovic, D. J. Hughes

The paper identifies a new function of ISG15 in stabilizing USP18 through non-covalent interactions, revealing a mechanism that controls type I IFN signalling.

bioRxiv · Jun 1, 2021 · PreprintImmunology

Direct antiviral activity of interferon stimulated genes is responsible for resistance to paramyxoviruses in ISG15-deficient cells

D. Holthaus, A. Vasou, C. G. Bamford, J. Andrejeva, C. Paulus, R. E. Randall, J. McLauchlan, D. J. Hughes

The paper shows that ISG15-deficient cells are resistant to paramyxovirus infection due to direct antiviral activity of ISGs, but prolonged IFN treatment causes resistance through translational inhibition.

bioRxiv · Dec 12, 2019Immunology