ImmunologybioRxiv
Genome-Wide CRISPR Screening Identifies BRD9 as a Druggable Component of Interferon-Stimulated Gene Expression and Antiviral Activity
J. Börold, D. Eletto, I. Busnadiego…·B. G. Hale
This study identifies BRD9 as a critical component of IFN signaling and antiviral activity through CRISPR screening, showing its druggability for targeting constitutive ISG expression.
DOI 10.15252/embr.202152823