Cancer BiologybioRxiv
Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation
DOI 10.1016/j.cmet.2023.10.003
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2 papers
Recent·Most cited
S. Skovsø, P. Overby, J. Memar-Zadeh…·J. D. Johnson
This study shows that beta-cell Cre expression and reduced Ins1 gene dosage protect NOD mice from type 1 diabetes, with Cre itself contributing additional protective effects.