Cancer BiologybioRxiv
Network analysis reveals a major role for 14q32 cluster miRNAs in determining transcriptional differences between IGHV-mutated and unmutated CLL
D. Bryant, L. Smith, K. R. Rogers-Broadway…·J. C. Strefford
The paper identifies 14q32 cluster miRNAs as key regulators of transcriptional differences between IGHV-mutated and unmutated CLL, with miR-409-3p and miR-411-3p repressing GAB1.
DOI 10.1038/s41375-023-01918-9