J. Carette

Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3

The paper reports the cryo-EM structure of SETD3 interacting with enterovirus protease 2A and shows that mutations in the SET domain reduce binding and protect against infection.

Impact of a Patient-Derived Hepatitis C Viral RNA Genome with a Mutated MicroRNA Binding Site

The paper shows that a single-nucleotide mutation in HCV RNA increases replication when miR-122 is low but reduces replication when miR-122 is high.