BiophysicsbioRxiv
Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3
C. E. Peters, U. Schulze-Gahmen, M. Eckhardt…·N. J. Krogan
The paper reports the cryo-EM structure of SETD3 interacting with enterovirus protease 2A and shows that mutations in the SET domain reduce binding and protect against infection.