Author

M. Eckhardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

G. M. Jang· 2 shared N. J. Krogan· 2 shared A. Choi· 1 shared A. Pitea· 1 shared C. E. Peters· 1 shared C. Hopf· 1 shared D. Abu Sammour· 1 shared D. Swaney· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

G. M. Jang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deep MALDI-MS Spatial Omics guided by Quantum Cascade Laser Mid-infrared Imaging Microscopy

L. Gruber, S. Schmidt, T. Enzlein, H. G. Vo, J. L. Cairns, Y. Ucal, F. Keller, D. Abu Sammour, R. Rudolf, M. Eckhardt, S. A. Iakab, L. Bindila, C. Hopf

This paper introduces a method combining quantum cascade laser infrared imaging with mass spectrometry to improve molecular identification in spatial omics, achieving high-resolution lipidomics profiling.

bioRxiv · Dec 14, 2023Biochemistry

HBV rewires liver cancer signaling by altering PP2A complexes

A. Pitea, R. Turnham, M. Eckhardt, G. M. Jang, Z. Xu, H. C. Lim, A. Choi, J. Von Dollen, R. S. Levin, J. T. Webber, E. McCarthy, J. Hu, X. Li, L. Che, G. Chan, , J. Gordan

This study identifies how HBV alters PP2A complexes to drive liver cancer signaling, revealing potential therapeutic targets.

bioRxiv · Mar 15, 2023 · PreprintCancer Biology

Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3

C. E. Peters, U. Schulze-Gahmen, M. Eckhardt, G. M. Jang, J. Xu, E. H. Pulido, M. Ott, O. Gozani, K. A. Verba, R. Hüttenhain, J. Carette, N. J. Krogan

The paper reports the cryo-EM structure of SETD3 interacting with enterovirus protease 2A and shows that mutations in the SET domain reduce binding and protect against infection.

bioRxiv · Jun 22, 2022Biophysics