Author

J. Castel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:metabolism & bioenergetics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. Martin· 2 shared C. Pham· 2 shared D. Li· 2 shared E. Foppen· 2 shared E. Montalban· 2 shared R. G. P. Denis· 2 shared R. Hassouna· 2 shared S. H. Luquet· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersPhysiology

C. Martin

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Author profile →

5 papers

Recent·Most cited

Genetic sex determination in three closely related hydrothermal vent gastropods, including one species with intersex individuals

J. Castel, F. Pradillon, V. Cueff, C. Daguin-Thiebaut, S. Ruault, J. Mary, S. Hourdez, D. Jollivet, T. Broquet

The paper investigates sex determination systems in three hydrothermal vent gastropods, finding a shared XY system but variable gonadal development in one species with intersex individuals.

bioRxiv · Apr 11, 2023Evolutionary Biology

Dual role of striatal astrocytes in behavioral flexibility and metabolism in the context of obesity

E. Montalban, D. Herrera Moro Chao, A. Ansoult, C. Pham, A. Contini, J. Castel, R. Hassouna, M. Hardonk, A. Petitbon, E. Foppen, G. Gangarossa, P. Trifilieff, D. Li, S. Luquet, C. Martin

This study shows that striatal astrocytes regulate behavioral flexibility and metabolism in obesity through chemogenetic manipulation in mice.

bioRxiv · Mar 21, 2023 · PreprintPhysiology

Mice with humanized livers reveal the involvement of hepatocyte circadian clocks in rhythmic behavior and physiology

A.-S. Delbes, M. Quinones, C. Gobet, J. Castel, R. G. P. Denis, B. Jeremy, B. D. Weger, E. Challet, A. Charpagne, S. Metairon, J. Piccand, M. Kraus, B. Rohde, J. Bial, E. M. Wilson, , S. H. Luquet

This study uses humanized mouse livers to show that peripheral circadian clocks can influence the central pacemaker, altering rhythmic behavior and physiology.

bioRxiv · Sep 8, 2022 · PreprintPhysiology

Hypothalamic astrocyte control systemic glucose metabolism and energy balance via regulation of extra-synaptic glutamate signaling

D. H. M. Chao, M. K. Kirchner, C. Pham, E. Foppen, R. G. P. Denis, J. Castel, C. Morel, E. Montalban, R. Hassouna, L.-C. Bui, J. Renault, C. Mouffle, C. Garcia-Caceres, M. H. Tschop, D. Li, , S. H. Luquet

This study shows that hypothalamic astrocytes regulate systemic glucose metabolism and energy balance through extra-synaptic glutamate signaling, offering new targets for obesity treatment.

bioRxiv · Feb 16, 2022 · PreprintPhysiology

Alteration of cardiolipin-dependent mitochondrial coupling in muscle protects against obesity

A. Prola, J. Blondelle, A. Ratnam-Vandestienne, J. Piquereau, R. Denis, S. Guyot, H. Chauvin, A. Mourier, M. Letheule, M. Maurer, C. Henry, N. Khadhraoui, G. Courtin, N. Blanchard-Gutton, L. Guillaud, , F. Pilot-Storck

This study identifies Hacd1 as a regulator of mitochondrial membrane composition in muscle, showing that reduced mitochondrial coupling protects against obesity.

bioRxiv · Jul 26, 2019 · PreprintCell Biology