Hypothalamic astrocyte control systemic glucose metabolism and energy balance via regulation of extra-synaptic glutamate signaling
D. H. M. Chao, M. K. Kirchner, C. Pham, E. Foppen, R. G. P. Denis, J. Castel, C. Morel, E. Montalban, R. Hassouna, L.-C. Bui, J. Renault, C. Mouffle, C. Garcia-Caceres, M. H. Tschop, D. Li, , S. H. Luquet
This study shows that hypothalamic astrocytes regulate systemic glucose metabolism and energy balance through extra-synaptic glutamate signaling, offering new targets for obesity treatment.
bioRxiv · Feb 16, 2022 · PreprintPhysiology