J. Cowgill

The paper presents cryo-EM structures of human HCN1 in different states to elucidate the structural basis for hyperpolarization-dependent opening of the channel.

This study presents cryo-EM structures of the human ρ1 GABAAR under different conditions, revealing structural mechanisms of gating and modulation with implications for pharmaceutical design.

This paper shows that hysteresis in Shaker potassium channel charge-voltage curves is eliminated with long test pulses, indicating it is a kinetic, not thermodynamic, phenomenon.

This study investigates the electromechanical coupling in HCN channels by simulating the interplay between voltage-sensor domains, pore regions, and membrane lipids.