Author

B. Chanda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:electrophysiology· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:cryo-EM· 1

Frequent Co-Authors

J. Cowgill· 3 shared V. Burtscher· 2 shared A. Elbahnsi· 1 shared A. V. Glukhov· 1 shared A. Warden· 1 shared C. P. Alvarez-Baron· 1 shared D. Lang· 1 shared D. Turner· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBiophysics

J. Cowgill

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Caveolar Compartmentalization is Required for Stable Rhythmicity of Sinus Nodal Cells and is Disrupted in Heart Failure

D. Lang, H. Ni, R. Medvedev, F. V. Liu, C. P. Alvarez-Baron, L. Tyan, D. Turner, A. Warden, S. Morotti, T. Schrauth, B. Chanda, T. J. Kamp, G. Robertson, E. Grandi, A. V. Glukhov

This study shows caveolae compartmentalize key proteins in SAN pacemaking, and their disruption leads to heart failure-related arrhythmias.

bioRxiv · Apr 14, 2024 · PreprintPhysiology

Structural Basis for Hyperpolarization-dependent Opening of the Human HCN1 Channel

V. Burtscher, J. Mount, J. Cowgill, Y. Chang, K. Bickel, P. Yuan, B. Chanda

The paper presents cryo-EM structures of human HCN1 in different states to elucidate the structural basis for hyperpolarization-dependent opening of the channel.

bioRxiv · Aug 17, 2023Biochemistry

Charge-voltage curves of Shaker potassium channel are not hysteretic at steady state

J. Cowgill, B. Chanda

This paper shows that hysteresis in Shaker potassium channel charge-voltage curves is eliminated with long test pulses, indicating it is a kinetic, not thermodynamic, phenomenon.

bioRxiv · Nov 7, 2022Biophysics

Interplay between VSD, pore and membrane lipids in electromechanical coupling in HCN channels

A. Elbahnsi, J. Cowgill, V. Burtscher, L. Wedemann, L. Zeckey, B. Chanda, L. Delemotte

This study investigates the electromechanical coupling in HCN channels by simulating the interplay between voltage-sensor domains, pore regions, and membrane lipids.

bioRxiv · May 20, 2022Biophysics

High-Throughput Single-Molecule Analysis via Divisive Segmentation and Clustering

D. White, M. Goldschen-Ohm, R. Goldsmith, B. Chanda

The paper introduces DISC, a platform that accelerates single-molecule trajectory analysis with divisive clustering, revealing a lack of cooperativity in HCN channel domains.

bioRxiv · Apr 9, 2019Biophysics