Cell BiologybioRxiv
The UPRmt Preserves Mitochondrial Import to Extend Lifespan
N. Xin, J. Durieux, C. Yang…·A. Dillin
This study shows that activating the UPRmt through ATFS-1 increases mitochondrial import efficiency, preserves import capacity with age, and extends lifespan in worms.
DOI 10.1083/jcb.202201071