Cancer BiologybioRxiv
Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response
R. Amin, A. Shukla, J. J. Zhu…·K. W. Hunter
This study identifies NUP210 as a metastasis susceptibility gene in ER+ breast cancer, showing its role in mechanosensation through heterochromatin-mediated disruption of mechanotransduction.