Author

J. Ernst

Primary ORCID profile (0000-0001-9951-6207 · 8 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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J. ErnstiD8 papers · University of California, San Francisco

Biology Disciplines

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Evolutionary Biology· 3

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:multiple species· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Haghani· 2 shared A. Seluanov· 2 shared A. T. Lu· 2 shared C. Z. Li· 2 shared J. Zhang· 2 shared K. Raj· 2 shared S. Horvath· 2 shared V. Gorbunova· 2 shared

Activity by Year

2017-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersEvolutionary Biology

A. Haghani

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3 papers

Recent·Most cited

Epigenetic predictors of species maximum lifespan and other life history traits in mammals

C. Z. Li, A. Haghani, Q. Yan, A. T. Lu, J. Zhang, Z. Fei, J. Ernst, X. Yang, V. N. Gladyshev, K. Raj, A. Seluanov, V. Gorbunova, S. Horvath

The paper develops DNA methylation predictors for mammalian maximum lifespan, gestation time, and sexual maturity, showing species-level epigenetic signatures that differ from individual lifespan variation.

bioRxiv · Nov 2, 2023 · PreprintEvolutionary Biology

DNA Methylation Networks Underlying Mammalian Traits

A. Haghani, A. T. Lu, C. Z. Li, T. R. Robeck, K. Belov, C. E. Breeze, R. T. Brooke, S. Clarke, C. G. Faulkes, Z. Fei, S. H. Ferguson, C. J. Finno, V. N. Gladyshev, V. Gorbunova, R. G. Goya, , S. Horvath

This study analyzes DNA methylation across 11,117 samples from 176 species to identify modules related to traits like age, lifespan, and phylogeny, revealing epigenetic patterns across evolution and aging.

bioRxiv · Mar 16, 2021Evolutionary Biology

Two C++ Libraries for Counting Trees on a Phylogenetic Terrace

R. Biczok, P. Bozsoky, P. Eisenmann, J. Ernst, T. Ribizel, F. Scholz, A. Trefzer, F. Weber, M. Hamann, A. Stamatakis

The paper introduces two C++ libraries that efficiently count and enumerate trees on a phylogenetic terrace using the SUPERB algorithm, outperforming a Python implementation.

bioRxiv · Nov 2, 2017Evolutionary Biology