BiophysicsbioRxivPreprint
Cryo-EM Structure of the Pol Polyprotein Provides Insights into HIV Maturation
J. J. E. K. Harrison, D. O. Passos, J. F. Bruhn…·E. Arnold
The paper determines the cryo-EM structure of the HIV-1 Pol polyprotein intermediate, revealing how RT dimerization activates proteolytic processing by bringing PR monomers together.