Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of The Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential
M. Sans, Y. Makino, J. Min, K. I. Rajapakshe, M. Yip-Schneider, C. M. Schmidt, M. W. Hurd, J. K. Burks, J. A. Gomez, F. I. Thege, J. Fahrmann, R. A. Wolff, M. P. Kim, P. A. Guerrero, A. Maitra
This study identifies NKX6-2 as a driver of gastric differentiation in IPMNs, linking its expression to indolent biological potential and progression.
Cancer Discovery · Jun 7, 2023Peer-reviewedCancer Biology