Author

E. Lengyel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Decio· 1 shared A. Gatto· 1 shared A. Mukherjee· 1 shared A. Murmann· 1 shared C. Battistini· 1 shared C.-Y. Chiang· 1 shared D. Bezwada· 1 shared D. Grapov· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. Decio

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemness

C. Battistini, H. A. Kenny, V. Nieddu, V. Melocchi, A. Decio, A. Gatto, M. Ghioni, F. M. Porta, R. Giavazzi, N. Colombo, F. Bianchi, E. Lengyel, U. Cavallaro

This study identifies FOXM1 as a microenvironment-induced factor that sustains ovarian cancer stemness and enhances response to Olaparib.

bioRxiv · Oct 30, 2023 · PreprintCancer Biology

Adipocytes reprogram glucose metabolism in cancer cells promoting metastasis

A. Mukherjee, D. Bezwada, M. Zandbergen, F. Francesco Greco, C.-Y. Chiang, M. Tasdemir, J. Fahrmann, D. Grapov, M. R. La Frano, H. S. Vu, J. W. Newman, L. A. McDonnell, L. Nezi, O. Fiehn, R. J. DeBerardinis, E. Lengyel

This study shows adipocytes reprogram cancer cell glucose metabolism to promote metastasis by increasing lipid synthesis via HIF1 regulation.

bioRxiv · Oct 17, 2022 · PreprintCancer Biology

The balance between toxic versus nontoxic microRNAs determines platinum sensitivity in ovarian cancer

M. Patel, Y. Wang, E. Bartom, R. Dhir, K. Nephew, D. Matei, A. Murmann, E. Lengyel, M. E. Peter

The paper shows that the ratio of toxic to nontoxic miRNAs in RISC predicts platinum sensitivity in ovarian cancer.

bioRxiv · Jan 24, 2021Cancer Biology