Cell BiologybioRxiv
Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high fat diet
J. A. Kellard, N. J. G. Rorsman, T. G. Hill…·L. Briant
This study shows that reduced somatostatin signaling in mice on a high fat diet leads to increased glucagon secretion, contributing to hyperglucagonaemia.
DOI 10.1016/j.molmet.2020.101021