Author

J. Halstead

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Physiology· 1

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Dillin· 1 shared A. E. Frakes· 1 shared C. P. Schneider· 1 shared E. Nyangau· 1 shared H. Mohammed· 1 shared H. Palacios· 1 shared L. Peng· 1 shared M. Hellerstein· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

A. Dillin

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1 paper

Recent·Most cited

Aging alters the metabolic flux signature of the ER unfolded protein response in vivo in mice

C. P. Schneider, L. Peng, S. Yuen, J. Halstead, H. Palacios, E. Nyangau, H. Mohammed, N. Ziari, A. E. Frakes, A. Dillin, M. Hellerstein

This study shows that aging in mice leads to an exaggerated and less effective endoplasmic reticulum unfolded protein response (UPRER) under stress, with altered metabolic flux patterns in protein synthesis and lipid production.

bioRxiv · Apr 14, 2021Physiology