Author

M. Hellerstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 3 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Dillin· 2 shared H. Palacios· 2 shared A. A. Mossakowski· 1 shared A. Bizieff· 1 shared A. Bukreyev· 1 shared A. Dunn· 1 shared A. E. Frakes· 1 shared A. J. Lutkewitte· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

A. Dillin

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Adipocyte lipin 1 is positively associated with metabolic health in humans and regulates systemic metabolism in mice.

A. LaPoint, J. M. Singer, D. Ferguson, T. M. Shew, K. RenKemeyer, H. Palacios, R. Field, M. Shankaran, G. I. Smith, J. Yoshino, M. He, G. J. Patti, M. Hellerstein, S. Klein, J. R. Brestoff, , A. J. Lutkewitte

The paper shows that lower adipose lipin 1 in humans correlates with metabolic issues, and mice lacking adipocyte lipin 1 develop metabolic disorders.

bioRxiv · Feb 1, 2023 · PreprintPhysiology

Increased remodeling and impaired adaption to endurance exercise in desminopathy

A. A. Mossakowski, H. T. Langer, A. Bizieff, A. M. Avey, H. Zbinden-Foncea, M. Hellerstein, K. Baar

This study examines the effects of endurance exercise on desminopathy in rats, finding impaired adaptation and worsened functional outcomes.

bioRxiv · Oct 3, 2021 · PreprintPhysiology

Aging alters the metabolic flux signature of the ER unfolded protein response in vivo in mice

C. P. Schneider, L. Peng, S. Yuen, J. Halstead, H. Palacios, E. Nyangau, H. Mohammed, N. Ziari, A. E. Frakes, A. Dillin, M. Hellerstein

This study shows that aging in mice leads to an exaggerated and less effective endoplasmic reticulum unfolded protein response (UPRER) under stress, with altered metabolic flux patterns in protein synthesis and lipid production.

bioRxiv · Apr 14, 2021Physiology

Dynamics and turnover of memory CD8 T cell responses following yellow fever vaccination

V. I. Zarnitsyna, R. S. Akondy, H. Ahmed, D. J. McGuire, V. G. Zarnitsyn, M. Moore, P. L. F. Johnson, R. Ahmed, K. Li, M. Hellerstein, R. Antia

This study uses mathematical models to show that memory CD8 T cells decline following a power law, with division rates stabilizing and death rates declining slowly over decades.

bioRxiv · Jan 23, 2021 · PreprintImmunology

A Novel SARS-CoV-2 Multitope Protein/Peptide Vaccine Candidate is Highly Immunogenic and Prevents Lung Infection in an AAV hACE2 Mouse Model and non-human primates

F. Guirakhoo, L. Kuo, J. Peng, J. H. Huang, B. Kuo, F. Lin, Y.-J. Liu, Z. Liu, G. Wu, S. Ding, K.-L. Hou, J. Cheng, V. Yang, H. Jiang, J. Wang, , C. Y. Wang

This paper describes a multitope protein-peptide vaccine candidate, UB-612, that is immunogenic and prevents lung infection in animal models, with ongoing clinical trials.

bioRxiv · Nov 30, 2020 · PreprintImmunology

Adhesion-mediated mechanosignaling forces mitohormesis

K. M. Tharp, R. Higuchi-Sanabria, G. Timblin, B. Ford, C. Garzon-Coral, C. Schneider, J. M. Muncie, C. Stashko, J. Daniele, A. S. Moore, P. Frankino, S. Manoli, H. Shao, A. L. Richards, K.-H. Chen, , V. M. Weaver

The paper shows that adhesion-mediated mechanosignaling activates a mitochondrial stress response through SLC9A1 and HSF1, altering mitochondrial function in aging and cancer.

bioRxiv · Mar 6, 2020Cell Biology