Regulation of Cardiomyocyte Adhesion and Mechanosignalling Through Distinct Nanoscale Behaviour of Integrin Ligands Mimicking Healthy or Fibrotic ECM
W. Hawkes, E. Marhuenda, P. M. Reynolds, C. O'Neill, P. Pandey, D. G. S. Wilson, M. Freeley, D. Huang, J. Hu, S. Gondarenko, J. Hone, N. Gadegaard, M. Palma, T. Iskratsch
This study investigates how integrin-ligand combinations affect cardiomyocyte adhesion, traction forces, and mechanosignalling in healthy and fibrotic ECM environments.
bioRxiv · Mar 13, 2022Cell Biology