Author

J. Irwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Jones· 2 shared R. Wells· 2 shared A. Alon· 1 shared A. Calderwood· 1 shared A. Kruse· 1 shared B. Roth· 1 shared B. Shoichet· 1 shared C. Dean· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersPlant Biology

M. Jones

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3 papers

Recent·Most cited

AlphaFold2 structures template ligand discovery

J. Lyu, N. Kapolka, R. Gumpper, A. Alon, L. Wang, M. Jain, X. Alvarez, K. Sakamoto, Y. Kim, J. DiBerto, K. Kim, T. Tummino, S. Huang, J. Irwin, O. Tarkhanova, , B. Roth

This study evaluates AlphaFold2 models for ligand discovery, finding they perform similarly to experimental structures despite conformational differences, and identify potent agonists for the 5-HT2A receptor.

bioRxiv · Dec 20, 2023 · PreprintPharmacology & Toxicology

Comparative transcriptomics identifies differences in the regulation of the floral transition between Arabidopsis and Brassica rapa cultivars

A. Calderwood, J. Hepworth, S. Woodhouse, L. Bilham, M. Jones, E. J. Tudor, M. Ali, C. Dean, R. Wells, J. Irwin, R. J. Morris

This study compares gene expression dynamics during floral transition in Arabidopsis and Brassica rapa, revealing differences in regulatory networks and synchronization of gene expression.

bioRxiv · Aug 26, 2020 · PreprintPlant Biology

Regulatory divergence of flowering time genes in the allopolyploid Brassica napus

M. Jones, N. Pullen, R. Wells, M. Trick, J. Irwin, R. Morris

This study examines how duplicated flowering time genes are regulated in Brassica napus, finding diverged expression patterns and cis-regulatory differences that impact gene retention.

bioRxiv · Aug 18, 2017Plant Biology