MicrobiologybioRxiv
TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction
H. Khan, H. Winstone, J. Jimenez-Guardeno…·M. Malim
This study shows that NCOA7 restricts SARS-CoV-2 infection by promoting endosomal acidification, and TMPRSS2 or removal of the furin cleavage site reduces this restriction.
DOI 10.1371/journal.ppat.1009820