Author

A. Davidson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Arazi· 2 shared B. Diamond· 2 shared C. Putterman· 2 shared D. J. Lieb· 2 shared D. Wofsy· 2 shared M. Kretzler· 2 shared N. Hacohen· 2 shared S. Li· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

A. Arazi

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Intrarenal myeloid subsets associated with kidney injury are comparable in mice and patients with lupus nephritis

P. Hoover, D. J. Lieb, J. Kang, S. Li, M. Peters, C. Raparia, A. Arazi, T. Eisenhaure, S. S. Gurajala, Q. Xiao, R. Mishra, M. Spurrell, R. Menon, M. Kretzler, J. Chen, , A. Davidson

This study identifies conserved myeloid subsets and disease-associated gene expression changes in kidney injury across lupus mouse models and human patients with lupus nephritis.

bioRxiv · Jun 24, 2023 · PreprintImmunology

Inhibition of Retinoic Acid Signaling in Proximal Tubular Epithelial cells Protects against Acute Kidney Injury by Enhancing Kim-1-dependent Efferocytosis

M. Yang, L. N. Lopez, M. Brewer, R. D. Delgado, A. A. Menshikh, K. A. Clouthier, Y. Zhu, T. Vanichapol, H. Yang, R. Harris, L. Gewin, C. R. Brooks, A. Davidson, M. de Caestecker

The paper shows that inhibiting RAR signaling in PTECs during AKI increases Kim-1 expression, which enhances efferocytosis and protects against injury.

bioRxiv · Jun 15, 2023 · PreprintPathology

Antibodies generated in vitro and in vivo elucidate design of a thermostable ADDomer COVID-19 nasal nanoparticle vaccine

D. Buzas, H. A. Bunzel, O. Staufer, E. Milodowski, G. Edmonds, J. Bufton, B. Vidana Matteo, S. Yadav, K. Gupta, C. Fletcher, M. Kavanagh Williamson, A. Harrison, U. Borucu, J. Capin, O. Francis, , I. Berger

This study develops a thermostable ADDomer-based nanoparticle vaccine that neutralizes SARS-CoV-2 and cross-reacts with VOCs, demonstrating its potential for nasal administration.

bioRxiv · Mar 17, 2023Biochemistry

TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction

H. Khan, H. Winstone, J. Jimenez-Guardeno, C. Graham, K. Doores, C. Goujon, D. Matthews, A. Davidson, S. Rihn, M. Palmarini, S. Neil, M. Malim

This study shows that NCOA7 restricts SARS-CoV-2 infection by promoting endosomal acidification, and TMPRSS2 or removal of the furin cleavage site reduces this restriction.

bioRxiv · Jul 23, 2021Microbiology

mTORC2 contributes to murine systemic autoimmunity

X. Zhou, H. Qi, M. Li, Y. Li, X. Zhu, S. Amin, A. Mariam, C. Diadhiou, A. Davidson, H. Zeng

This study shows mTORC2 promotes Tfh differentiation and disrupts Treg homeostasis, contributing to systemic autoimmunity, and suggests mTORC2 as a potential therapeutic target.

bioRxiv · Mar 27, 2021 · PreprintImmunology

The immune cell landscape in kidneys of lupus nephritis patients

A. Arazi, D. A. Rao, C. C. Berthier, A. Davidson, Y. Liu, P. J. Hoover, A. Chicoine, T. M. Eisenhaure, A. H. Jonsson, S. Li, D. J. Lieb, E. P. Browne, A. Noma, D. Sutherby, S. Steelman, , B. Diamond

This study uses single-cell RNA-seq to analyze immune cell subsets in lupus nephritis kidneys, identifying pro-inflammatory and resolving responses and potential therapeutic targets.

bioRxiv · Jul 7, 2018Immunology