Author

J. Jude

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

J. Zuber· 2 shared A. Cantoran-Garcia· 1 shared A. Schlattl· 1 shared C. P. Santos· 1 shared F. X. Real· 1 shared G. A. Versteeg· 1 shared G. Wutz· 1 shared H. Kovar· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

J. Zuber

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2 papers

Recent·Most cited

SPOP targets the immune transcription factor IRF1 for proteasomal degradation

M. Vunjak, I. Schwartz, A. Cantoran-Garcia, M. Mastrovito, M. Hinterndorfer, M. de Almeida, V. Budroni, J. Wang, K. Froussios, J. Jude, T. Decker, J. Zuber, G. A. Versteeg

This study identifies SPOP as an E3 ligase that targets IRF1 for proteasomal degradation, highlighting its role in regulating IRF1 levels to balance immune response and tumor suppression.

bioRxiv · Oct 10, 2022Cell Biology

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts

P. van der Lelij, S. Lieb, J. Jude, G. Wutz, C. P. Santos, K. Falkenberg, A. Schlattl, J. Ban, R. Schwentner, T. Hoffmann, H. Kovar, F. X. Real, T. Waldman, M. Pearson, N. Kraut, , M. P. Petronczki

The paper identifies a synthetic lethal relationship between STAG1 and STAG2 in cancers, showing STAG1 inactivation selectively targets STAG2-mutated cancer cells.

bioRxiv · Jun 25, 2017Cancer Biology