Author

J. L. Barth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

J. F. Gainor· 2 shared M. Mino-Kenudson· 2 shared A. Acker· 1 shared A. Do· 1 shared A. Lawless· 1 shared A. N. Hata· 1 shared A. Shiba-Ishii· 1 shared A. Tirard· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

J. F. Gainor

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor

S. M. Blum, D. A. Zlotoff, N. P. Smith, I. J. Kernin, S. Ramesh, L. Zubiri, J. Caplin, N. Samanta, S. C. Martin, A. Tirard, P. Sen, Y. Song, J. L. Barth, K. Slowikowski, M. Nasrallah, , A.-C. Villani

This study identifies immune cell types and biomarkers in irMyocarditis using single-cell RNA sequencing and TCR analysis across heart, blood, and tumor tissues.

bioRxiv · Sep 15, 2023 · PreprintImmunology

Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis

C. Shiau, J. Cao, M. T. Gregory, D. Gong, X. Yin, J.-W. Cho, P. L. Wang, J. Su, S. Wang, J. W. Reeves, T. K. Kim, Y. Kim, J. A. Guo, N. A. Lester, N. Schurman, , W. L. Hwang

This study uses single-cell spatial transcriptomics and optimal transport analysis to reveal therapy-induced changes in pancreatic cancer microenvironment interactions.

bioRxiv · Jun 28, 2023 · PreprintCancer Biology

Structural and functional analysis of lorlatinib analogs reveals roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer

A. Shiba-Ishii, T. W. Johnson, I. Dagogo-Jack, M. Mino-Kenudson, T. R. Johnson, P. Wei, S. L. Weinrich, M. A. McTigue, M. A. Walcott, L. Nguyen-Phuong, K. Dionne, A. Acker, L. Kiedrowski, A. Do, J. L. Peterson, , A. N. Hata

This study identifies lorlatinib-resistant ALK mutations and evaluates analogs to develop targeted therapies for compound resistance in ALK-positive lung cancer.

Nature Cancer · Jun 20, 2022Peer-reviewedCancer Biology

Transcriptomic characterization of signaling pathways associated with osteoblastic differentiation of MC-3T3E1 cells

L. M. Luttrell, M. S. Dar, D. Gesty-Palmer, H. M. El-Shewy, K. M. Robinson, C. J. Haycraft, J. L. Barth

The paper characterizes signaling pathways involved in osteoblastic differentiation of MC-3T3E1 cells using gene expression data and pathway analysis.

bioRxiv · Sep 6, 2018Cell Biology